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ENALAPRIL MALEATE INTERMEDIATES
[Chemical Name]: (aS,4S)-4-Methyl-2,5-dioxo-a-(2-phenylethyl)-3-oxazolidineaceticacid, ethyl ester
[Synonyms]: Ethyl (S)-2-[(S)-4-methyl-2,5-dioxo-1,3-oxazolidin-3-yl]-4-phenylbutyrate
[Structure]:
[Formula]: C16H19NO5
[Molecular Weight]: 305.33
[CAS RN]: 84793-24-8
[Density]: 1.223 g/ cm3
[Optical Rotation]: [a]20D = +36.5°(HCCl3, c 1.00)
[Specification]:
| Appearance |
White crystalline powder |
| Solubility |
Freely soluble in acetone acetonitrile |
| Specific rotation |
+36.5°(HCCl3, c 1.00) |
| Melting point |
68～72℃ |
| Loss on drying |
0.5%max |
| N-[1-(S)-ethoxycarbonyl-3-phenylpropyl]-L-alanine |
1.0%max |
| Cyclohexyl analog of alanine |
0.3%max |
| Total unknown impurities |
2.0%max |
| Purity HPLC |
98.0%min |
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