Mitotane (o,p'-DDD)
[Chemical Name]:
1,1-Dichloro-2,2-bis(2,4'-dichlorophenyl)ethane; 1,1-Dichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane
[Depression]:
A derivative of the insecticide DICHLORODIPHENYLDICHLOROETHANE that specifically inhibits cells of the adrenal cortex and their production of hormones. It is used to treat adrenocortical tumors and causes CNS damage, but no bone marrow depression.
[Structure]:
[Formula]:C14H10Cl4
[Molecular Weight]:320.045
[CAS RN]:53-19-0
[Specification]:USP27/USP28
Appearance |
White or off white |
| Identification |
|
A |
IR chromatograph conforms to characteristic peak of RS |
B |
UV chromatograph conforms to characteristic peak of RS |
Melting range°C |
75~81°C |
Loss on drying |
0.5%max |
Residue on ignition |
0.5%max |
Organic volatile impurities |
Meets the requirements |
Assay (calculated on dried basis C14H10Cl4) |
97.0~103.0% |
|
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